Headache disorders are common, debilitating, and in many cases inadequately managed by existing treatments. There are over 200 different kinds of headaches recorded to date, and each comes with its own symptoms, causes and treatments. Some can be extreme and chronic, such as cluster headaches.
Although clinical trials of cannabis for neuropathic pain have shown promising results, there has been limited research on its use specifically for headache disorders.
One recent review considers historical prescription practices, summarizes the existing reports on the use of cannabis for a headache, and examines the preclinical literature exploring the role of exogenous and endogenous cannabinoids to alter headache pathophysiology.
Currently, there is not enough evidence from well-designed clinical trials to support the use of cannabis for a headache, but there are sufficient anecdotal and preliminary results, as well as plausible neurobiological mechanisms, to warrant appropriately designed clinical trials.
Such trials are needed to determine short- and long-term efficacy for specific headache types, compatibility with existing treatments, optimal administration practices, as well as potential risks.
The present review examines the historical guidelines for cannabis treatment of a headache, available clinical data on the use of cannabis for a headache, and preclinical literature on the role of the endocannabinoid system in headache pathophysiology.
From this examination, various methodological recommendations are made for future studies and potentially novel treatment practices are considered. Although placebo-controlled clinical trials are still needed to appropriately determine efficacy, it appears likely that cannabis will emerge as a potential treatment for some headache sufferers.
Preclinical and clinical trials are being conducted more and more as time goes on. While CBD is available to purchase around the world (if it’s derived from hemp) be sure to consult your doctor before you use it. If you want to use it to treat an ailment, it’s crucial to ask your doctor, especially as, like all medication, it may counteract.
Here is the full scientific article if you wish to download it.