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Cannabinoids are a group of chemicals derived from the marijuana plant (cannabis sativa). Cannabidiol (CBD) is one of these compounds and studies have suggested that it has anti inflammatory properties to treat animals with nervous system problems. Tetrahydrocannabinol (THC) is another one of these compounds that wields a psychoactive effect in animals.
Cannabinoid receptors (CB1 and CB2) are found in the endocannabinoid system and allow cannabinoids to bind and do their job in the body. The paper describes the most recent developments in the knowledge of medical cannabis’ effects at molecular basis and also how the CB1 and CB2 receptors were discovered.
Here is the full scientific article if you wish to download it.
The proposed effects of cannabis treat pain and muscle spasms, have led to medical marijuana being used to treat the symptoms of multiple sclerosis and muscle stiffness in long term ms patients. The use of THC as an anti nausea substance for cancer chemotherapy, and as an appetite upper drug, is being slowly realized. Clinical studies in multiple sclerosis (MS), might lead to the legitimization of THC as a remedy for this syndrome.
Recent studies with cannabidiol (CBD) in animals with rheumatoid arthritis have lead to the idea of clinical investigations occurring. A synthetic cannabinoid, HU-211 (Dexanabinol), is in development in the clinical stages of investigation as a neuroprotectant for head trauma. This may lead to cannabis being legalized to treat numerous human conditions.
Cannabinoids are currently in use for the bettering of appetite in HIV patients and for the stopping of nausea and vomiting that is brought on by cancer chemotherapy. In the future, cannabinoids may be legalized to reduce the serious problems arising from MS related syndromes such as muscle spasticity.
It might be possible that CBD will be made into a substance for the treatment of rheumatoid arthritis. HU-211 has been successful in trials relating to neuroprotection, and if this drug passes all the trials, synthetic cannabinoids may be used for head injury and maybe for the reduction of stroke damage.