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The endocannabinoid system (ECS) is both in your brain and other parts of your body. The ECS has been linked to heart failure, clinical shock, cardiovascular risk in obesity, diabetes, and metabolic syndrome. The ECS is also known to affect inflammation and healing functions. This paper focuses on the potential use of the ECS in therapies for various cardiovascular disorders related to inflammation and tissue injury. They include myocardial infarctions (heart attacks), heart failure, atherosclerosis and cardiometabolic disorders. The investigation covers both THC and CBD.
In anesthetized or hypertensive (high blood pressure) individuals, this effect is stronger. It causes the heartbeat so slow (bradycardia) and can lower blood pressure. Though this depends on many factors. Acute use of THC increases the heart rate – for example, irregular, occasional consumption. Chronic use (regular and steady), leads to a lower heart rate. This aspect is complicated, however, and further research is needed on the topic.
Here is the full scientific article if you wish to download it.
For the models used in the research, CBD treatment showed the ability to reduce inflammation in heart muscle and to improve some heart functioning after the damage. The models investigated had undergone ischemia-reperfusion. This is damage caused when blood returns to the tissue after a period without blood-flow or oxygen. The authors stressed that the mechanism for this protection was difficult to understand.
The authors mention another study with regards to the protective functions of CBD. In that study, CBD inhibited all the damage to the coronary artery cells caused by high-glucose levels in diabetic patients. On further investigation, they suggested that CBD may also be beneficial for other disorders such as atherosclerosis. This is because the mechanisms that CBD interacts with follow multiple routes. This is also why CBD is considered a good therapy when other treatments prove ineffective.