The Anti-Inflammatory Effect of CBD on Sebum Glands | cannabisMD

The Anti-Inflammatory Effect of CBD on Sebum Glands

The Journal of Clinical Investigation

In this study, Cannabidiol (CBD) was investigated as a treatment for acne vulgaris. The theory behind this involves numerous different properties of CBD. The researchers stated that the current problem with treatments for acne is that there are many different factors involved in its development. CBD seems to be able to tackle each of these different aspects simultaneously.

CBD Reduces the Production of Fats and Oils by Skin Cells

When investigated, CBD reduced the production of sebum by skin cells. This wasn’t by a single pathway (the endocannabinoid system) as was expected, but appeared to cover a more “universal” approach. This means CBD was able to reduce sebum production from a variety of angles.

CBD Reduced the Unwanted Growth of Sebocytes

In vitro, which means, “in glass” (test tubes), CBD was seen to reduce the growth/division of sebocytes. Sebocytes are the cells that produce sebum. However, rather than killing the cells, it just slowed growth and division. This means the number of sebocytes did not increase or decrease. This reduction in the number of sebocytes also would prevent an unwanted increase in skin sebum production that would lead to acne.

CBD Is a “Universal Anti-Inflammatory”

Many studies have identified CBD as a good anti-inflammatory (in some cases, even better than aspirin). With regards to acne, CBD prevented “pro-acne” inflammation. Inflammation of sebocytes can result in acne, so this further solidifies CBD as a good anti-acne treatment. You’ll have seen the inflammation associated with acne before. For those suffering from acne, they’ll sometimes have red, tender areas around the outbreaks.

Anti-Inflammatory Effect CBD Sebum Glands

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