THC and Their Potential in Glioblastoma Multiforme Treatment | cannabisMD

THC and Their Potential in Glioblastoma Multiforme Treatment

THC and Their Potential in Glioblastoma Multiforme Treatment

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Cannabinoids are found in the cannabis plant and have range of constituents including tetrahydrocannabinol (THC) and cannabidiol (CBD). These constituents are said to reduce tumor growth in animal models and their effectiveness as antitumor drugs has been studied extensively, although they have never been tested on humans. This paper will assess the cannabinoids anti tumoral effects in a trial with 9 humans who have recurrent glioblastoma multiforme (GBM).

Here is the full scientific article if you wish to download it.

Main Points

  • THC can cause adverse psychoactive effects
  • THC is a safe anti tumor drug

THC can cause adverse psychoactive effects

THC has been shown to cause adverse psychotropic effects in anecdotal trials in patients with these tumors. It has been seen that dosing THC at wrong levels to the appropriate amount can actually reverse the healing process and progress cell growth in malignant cells.

THC is a safe anti tumor drug

Each of the patients were administered with medical cannabis when it was shown that their normal medication did not work and tumour growth progressed. It was shown that the THC was delivered in a safe manner and could be applied without adverse psychoactive effects. THC was able to inhibit tumor cell proliferation and decreased tumour cells by immunosuppression in 2 of the patients. More studies will need to follow to evaluate the full potential of its antitumor properties and into the treatment of glioma tumors.

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