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Leptin as a potential therapeutic target for breast cancer prevention and treatment
Cannabinoids are a group of chemicals that come from the cannabis plant (cannabis sativa). Cannabidiol (CBD) is one of these chemicals and studies have suggest that it has anti inflammatory effects when induced in animals. Tetrahydrocannabinol (THC) is another one of these compounds that wields a psychotropic effect in animals. Cannabinoid receptors (CB1 and CB2) are found in the endocannabinoid system and allow cannabinoids to bind and do their job in the body. This paper will review Leptin, a synthetic cannabinoid, and its role in the prevention of breast cancer.
Cannabinoids have a potential to halt breast cancer development
Obesity is said to be a detrimental risk factor for postmenopausal breast cancer. Increased estrogen levels are said to be a growth condition related to this relationship. However, there is growing evidence that conditions made directly in adipose tissue, adipokines, can also have an impact on breast cancer growth. Leptin, a synthetic cannabinoid, is found in serum/plasma in growing amounts as body weight/body fat gets bigger. This review has given a good insight in the important properties in leptin, and its relationship in mammary/breast tumor development.
Cannabinoids have therapeutic benefit in breast cancer patients
Cannabinoids have been seen to have a therapeutic effect on patients with breast cancer as CBD has been proven to have anti inflammatory properties, which aids tumour desizing. This report involves discoveries from human and animal studies. knowledge on leptin-associated chemicals which may have therapeutic potential is evaluated. More so, plans to change serum leptin levels by dietary and pharmacological interventions are talked about. The reader will receive knowledge into the interactions of an adipose tissue protein and its possible job in breast cancer advancement as well as ways to fuel leptins actions. More studies are needed to see if interfering with the mechanism of leptin has preventive or therapeutic uses in breast cancer.