Synthetic Cannabinoids as a Possible Treatment for Breast Cancer? | cannabisMD

Synthetic Cannabinoids as a Possible Treatment for Breast Cancer?

Synthetic Cannabinoids as a Possible Treatment for Breast Cancer?

Cannabinoids are derived from the cannabis plant and have anti-inflammatory effects. This has led to a huge amount of research being carried out in the area of cannabinoids as they may possess antitumorigenic properties. Cannabidiol (CBD) is a constituent of cannabinoids and not much is known about their ability in halting breast cancer cell growth.

Cannabinoid receptors are located in the endocannabinoid system and they allow cannabinoids to carry out their business. This study will review the ability of medical cannabis to treat different types of breast cancer in animal models.

Here is the full scientific article if you wish to download it.

Main Points

  • Synthetic cannabinoid (WIN-55,212-2) can inhibit cell proliferation
  • Synthetic cannabinoid (JWH-133) can inhibit cell proliferation

Synthetic cannabinoid (WIN-55,212-2) can inhibit cell proliferation

Cannabinoid receptors 1 and 2 have been shown to be overexpressed in breast tumors when compared with normal breast tissue. This means that these receptors can be agonized with a cannabinoid to promote apoptosis (cell death). This study has shown that a CB2 synthetic cannabinoid agonist (WIN-55,212-2) can inhibit cell proliferation. This was shown in mice who were treated with this agonist. A 50 % decrease in tumor growth was recorded in this case.

Another agonist (JWH-133), was reported to delay mammary gland tumors in mice. These results show that CB1 and CB2 receptors could be developed further to be used as a therapeutic to fight breast cancer growth. This is the first time that medical marijuana was reported to show significant anti-tumoral growth in different mouse model systems. This is huge for the cannabis oil industry as its products may have the ability to treat forms of cancer, including lung cancer, with little known side effects.

If you wish to use medical cannabis or CBD as a form of treatment, make sure that you first consult your doctor before you do so.

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