As chemical-engineered cannabinoid medications become more readily available, we still face the ongoing dismissal of medical marijuana.
Insys Therapeutics is an Arizona based specialty pharmaceutical company that isn’t shy about their core mission. Their website speaks heavily of patient-care, community, and social responsibility. Insys seeks to improve the quality of patient care by researching, designing, and marketing novel drug application and delivery systems and cannabinoids. They want to address unmet patients needs. Their on-the-market medications have been approved by the Food and Drug Administration (FDA).
Insys has two medications on the market: Subsys and Syndros. Subsys is for pain in 18+ cancer patients when traditional opioid-based painkillers no longer work. It is ingested via a spray. Since 2014, according to IMA, Sybus been prescribed more than any of transmucosal immediate-release fentanyl product.’ll speak to the uses of Syndros, their other on-the-market product more extensively below but, in essence, it’s made of a liquid formulation of dronabinol (a THC-mimic cannabinoid) and is taken as an oral solution.
Insys currently has six drugs in development in ongoing clinical trials. One is an oral solution of cannabidiol intended to treat childhood absence epilepsy, infantile spasms, and Prader-Willi syndrome. Another is dronabinol-based, but unlike Syndros, it will be introduced to the body through inhalation for treating anorexia in cancer (low to no appetite during chemotherapy) and agitation in Alzheimer’s disease.
Insys Therapeutics also have four new sprays in the development: Buprenorphine, for moderate-to-severe-to-acute pain; Buprenorphine or Naloxone, for opioid dependence; Epinephrine, for anaphylactic reaction; and Naloxone for opioid overdoses.
Part of Insys’ framework, as they present it on their website at least, is deeply concerned with the social wellbeing of their local community. The website asserts: “At Insys, we believe in doing the right thing–for patients, customers, employees, communities, and business partners. They claim to serve thousands of people in their local community.
The company is so openly dedicated they have a form offer aid, stating “if you’d like us to get involved with your organization or cause, please fill out the form” with an attached digital email sender.
Syndros is FDA approved liquid dronabinol. It’s a lab-made or chemically-engineered version of Tetrahydrocannabinol (THC). Syndros is a controlled substance (CII/ Schedule II) because it contains dronabinol. Dronabinol can be a target for abusers of prescription medication or street drugs. Only a doctor can prescribe Syndros, and if you have a prescription Insys warns to hide your medication in a safe place to protect from theft.
They also warn that it is illegal to sell or give away your Syndros as it can cause death or harm. Most available medications don’t always effectively stimulate the appetite of AIDS patients which is essential to offer some normalcy and comfort in their daily life. More than 90,000 HIV/AIDS patients experience weight loss and Syndros is one of the newer options for restabilizing appetite.
Syndros is a liquid oral solution, the first and only, of dronabinol, for patients who prefer liquid medications. Syndros is for anti-cancer treatment or chemotherapy-induced nausea and vomiting (CINV), whose condition hasn’t improved with opioid-based anti-nausea medicines. Syndros is also for AIDS patients with anorexia (low to no appetite) who have experience related weight loss.
Serious side effects include seizures, or drug and alcohol abuse. Contact your doctor immediately if you have a seizure or are having addiction problems. You may also experience increased irritability, nervousness, restlessness.
The most common side effects are stomach-area (abdominal) pain, dizziness, feeling euphoria, nausea, overly suspicious or feeling people want to harm you (paranoid reaction), sleepiness, abnormal thoughts, and vomiting. If your nausea, vomiting, or abdominal pain gets worse, or does not decrease, tell your doctor immediately.minal) pain, dizziness, feeling euphoria, nausea, overly suspicious or feeling people want to harm you (paranoid reaction), sleepiness, abnormal thoughts, and vomiting. If your nausea, vomiting, or abdominal pain gets worse, or does not decrease, tell your doctor immediately.