Multiple Sclerosis (MS) is a disease of the central nervous system (CNS). This mean it affects the brain and spinal cord. It involves nerve damage. The damage causes communication problems between the brain and overall body.
Central pain relating to spasticity is common and typically refractory in multiple sclerosis. It can be difficult to treat. A team of doctors, David J. Rog, BMBS; Turo J. Nurmiko, PhD; Tim Friede PhD, and Carolyn A Young M.D. “conducted a single-center, 5 week…randomized, double-blind, placebo-controlled, parallel-group trial in 66 patients with Multiple Sclerosis (MS) and related central pain” using a cannabis-based medicine (CBM).
Here is the full scientific article if you wish to download it.
The CBM contained Δ⁹-tetrahydrocannabinol (THC) and Cannabidiol (CBD) THC and CBD. It was delivered through an oromucosal spray. It’s purpose was to purpose as an adjunctive analgesic treatment, which means a pain relieving therapy.
It entailed a 1-week run-in and 4 weeks of treatment.There was 2.7 mg of THC and 2.5 mg of CBD per spray. Patients were allowed to gradually increase their dosage to 48 sprays over the span of 24 hours.
Ultimately, 97% of patients (64 patients) finished the trial. 34 of which actually received CMD. Pain and sleep disturbance was recovered daily. They used an 11-point numerical rating scale. CMD was superior to the placebo. CBD was also generally well-tolerated. More patients, however, reported minor adverse side effects like dizziness, dry mouth, and drowsiness with CBM over the placebo.
They have added to the ongoing investigated on the efficacy, safety ,and tolerability of a cannabis-based medicine, containing delta-9 tetrahydrocannabinol and cannabidiol, treats spasticity in MS. The primary efficacy analysis on the intention to treat population showed the active preparation to be significantly superior. Secondary efficacy measures were all in favour of active preparation but did not achieve statistical significance.
If you are interested in using medical cannabis to treat MS, you should first and foremost consult your regional laws. You should do so to assure you don’t break the law. Cannabis is still outlawed medically in many states and countries. You should also speak to your doctor, as you’ll require a prescription and your doctor is most qualified to advise you.