There is a great need for safe and effective therapies in the management of refractory childhood epilepsy, especially in the context of potentially devastating epileptic encephalopathies such as infantile spasms and Lennox-Gastaut syndrome.
Despite somewhat limited preclinical and epidemiologic evidence and a lack of well-designed clinical trials, cannabidiol-as well as CBD-enriched whole plant extracts-has generated enormous interest as a potential treatment for epilepsy, most notably in the setting of Dravet syndrome.
Here is the full scientific article if you wish to download it.
Online forums are replete with seemingly miraculous responses to CBD after the failure of numerous mainstream medical and surgical therapies. Of note, there is significant debate as to the relative potential value of CBD-enriched whole plant extracts versus purified or synthetic preparations of CBD.
Clinical trials of multiple cannabidiol preparations are eagerly anticipated. At face value, this study indicates that CBD-containing products might be useful and well tolerated in the treatment of multiple forms of refractory childhood epilepsy. Rigorous clinical trials are clearly warranted and supported by these findings to determine the efficacy and safety of CBD. More broadly, the potential efficacy of CBD should be evaluated in children with less refractory epilepsy syndromes as well as in adults, especially as there are no data indicating age or syndrome specificity.
Given the ease with which CBD products are obtained in many parts of the world as well as the medical and even legal risks that presently accompany their use-practitioners, patients, and parents must proceed with caution and make efforts to distinguish between hope and empirical evidence.
Parents in the UK with children suffering from epilepsy have been protesting to be able to receive THC rich cannabidiol to treat their children. The problem here is that it is totally illegal so parents have no other choice but to treat their children overseas. If you wish to use or recommend medical cannabis,make sure to first speak with your doctor and do your research before doing so.