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Marijuana has been smoked recreationally and medicinally for hundreds of years. The main psychoactive parts of cannabis, tetrahydrocannabinol (THC), triggers the CB1 cannabinoid receptors. CB1 receptor agravators may help alleviate some of the problems arising from a wide variety of human diseases. Doses of THC can provide a therapeutic feeling to its user but also a psychoactive element. This causes adverse effects in the users behaviour pattern, and the main cannabis culprits of these side effects are K2 and Spice. This paper will look at the most recent and future therapeutic uses of Cannabinoid receptor agonists and also describes K2 and spice phenomenon. This will then give the reader an opportunity to have their own opinion if cannabis should be deemed a drug of abuse or if it has therapeutic potential in humans to treat chronic pain, multiple sclerosis, pain from nausea and better mental health.
Here is the full scientific article if you wish to download it.
Cannabinoids have a therapeutic potential
Although marijuana has been smoked for hundreds of year, the view that THC triggers CB1 receptors lead to a growing interest in the development of cannabis as therapeutics. Cannabis comes with a downfall as it stimulates a psychoactive effect in its users, and this has slowed down studies into its mechanisms of action. Studies are now taking place of how to get rid of the unwarranted side effects, such as the development of cannabinoid receptor agonists and its limited ability in the central nervous system, and the use of natural cannabinoid receptors agonists.
Spice and K2 are dangerous
Scientists have attempted to make a cannabinoid 1 receptor agonist in the lab to better cannabis’ therapeutic potential, but this lead to a highly dangerous drug of abuse called K2 and spice. These drugs produce an even stronger physco tropic effect then natural cannabis. The THC structure was altered in these drugs and it caused patients to have quite serious adverse conditions, such as addiction and schizophrenia. This study suggested that scientists need to take their time to realise it’s full toxic properties. Future studies will be vital for the education of communities and lawmakers in working together with the public’s health at their best interest.
There will be plenty of problems that will arise when developing cannabinoids in the lab as they have several adverse effects in patients. Making matters worse is the current view that numerous experimental chemicals are being used as designer drugs that can avoid detection and regulation. Although there are massive public health problems that are related to with any addictive substance, this paper suggests that the potential therapeutic uses of cannabis can overshadow the negative problems. This has lead to the belief that cannabis based drugs are actually worth a decent study effort to learn about their properties in detail. This will then allow people to discover the pharmacodynamic and potential clinical side effects.