How Anxiety can be Potentially Treated by Cannabinoids | cannabisMD

How Anxiety can be Potentially Treated by Cannabinoids

Cannabinoids are a collection of compounds that are situated in the marijuana plant (cannabis sativa). Cannabidiol (CBD) is the main chemical within the cannabis plant and it is said by the wide scientific company that it has anti inflammatory effects when induced into animal cells. Tetrahydrocannabinol (THC) is another one of these chemicals and it is said to have a psychotropic effect. Cannabinoid receptors (CB1 and CB2) are located in the endocannabinoid system and gives cannabinoids power to bind and thrive in the body. This paper will look at how cannabinoids can be used in the brain to alleviate anxiety.

Here is the full scientific article if you wish to download it.

Main Points

  • Cannabinoids may facilitate extinction learning
  • Selective cannabinoids for certain patients need to be identified

Cannabinoids may facilitate extinction learning

This paper focuses on the part the cannabinoid system plays in eradicating fear in learning and retention. The paper looks at what neural circuits are controlling fear extinction, how can fear extinction be made more effective and what role does the cannabinoid system have. The paper has found that by expanding cannabinoid transmission, extinction learning can be facilitated and that the cannabinoid system is a potential target for cannabinoid receptor agonists.

Selective cannabinoids for certain patients need to be identified

Current treatments (selective serotonin reuptake inhibitors) for anxiety disorders, such as PTSD, seem to wear off after the body has built up a tolerance for them and the patients have to continue to deal with their anxiety. New treatments are desperately needed for selective patients. As mentioned before, modulation of the cannabinoid system can result in learning and retention of fear extinction. THC was seen to condition fear and enhance memories in humans. The cannabinoid receptor 1 seemed to improve fear extinction training when induce with a cannabinoid agonist. This could be massive for people suffering with anxiety because cannabinoids are a side effect free medicine that could reduce anxiety symptoms if acutely dosed.

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