Cannabinoids are chemical compounds that react within the endocannabinoid system of the human body and other animals. Cannabinoids interact with cannabinoids receptors (CB) which have recently been discovered. The most common known today are the CB1 and CB2 receptors. CB1 receptors are found primarily within the brain. CB2 receptors are also found there but in lesser quantities The majority of CB2 receptors are mostly found throughout the body i.e. the immune sysmtem, the nervous system and organs.
Cannabinoids come in three forms which are synthetic cannabinoids (Man Made, Highly Illegal, Mainly Used For Testing), endocannabinoids (created naturally within our bodies) and phytocannabinoids (come from plants). Introducing cannabinoids to your body allows them to interact and stimulate the the CB receptors within the endocannabinoids systems whose responsibility it is to provide balance within the body. For example helping with Gastrointestinal Disease.
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If there is an increase in inflammation or other issue the endocannabinoid system will do its best along with the immune system etc to treat the bodies aliments naturally. Introducing phytocannabinoids such as THC or CBD from the cannabis plant and hemp plant (CBD Only) are said to “top up” or influence your body to balance out in a more natural way. Using cannabinoids such as CBD or THC have been found to reduce inflammation in this way.
The Potential of Cannabinoids Treating Gastrointestinal Diseases
The three most influential cannabinoids from the cannabis plant are THC (Tetrahydrocannabinol), CBD (Cannabidiol) & CBN (Cannabinol) out of over a hundred cannabinoids present within it. THC is known for its psychoactive effects but is understood to be able to provide potential neurological benefits as a result i.e. calming those with disorders like ADHD or even bipolar disorder.
CBD takes up most of the cannabis plant and provides most of the benefits as a result. Sadly the use of its oils is still illegal in some states within the US even though it doesn’t get you high. This is the cannabinoid which can provide the most potential benefits for gastrointestinal diseases as it is widely known to provide anti-inflammatory properties. CBN is the result of THC metabolizing.
This has been discovered mostly when THC and CBD are used together. In other words the patients can receive all the benefits of THC and CBD without the psychoactive effects because CBD stops this.
As mentioned before, the CB2 receptors are more prevalent within the body as a whole with some presence in the brain. This means in theory to stimulate these receptors within the endocannabinoids system would bring balance to the body for a specific ailment (gastrointestinal diseases) and would be very beneficial. Furthermore because CBD has be found to interact with these receptors it would be correct to suggest that using CBD could help with gastrointestinal related issues, and that is what this study suggests.
The anti-inflammatory properties of CBD communicate with the CB2 receptors within the endocannabinoid system to provide a pathophysiological benefit. While it will not cure the cause of the aliment, cannabinoids (CBD) can at least make our bodies react in a more balanced way while treating. This could in turn provide pain relief and relieve other irritable symptoms of gastrointestinal diseases. These benefits have been similarly viewed when using cannabis with cancer patients going through chemotherapy. The cannabinoids of cannabis are known to help with nauseous feelings and vomiting caused by the chemotherapy.