Cannabis in the Treatment of Multiple Sclerosis | cannabisMD

Cannabis in the Treatment of Multiple Sclerosis

multiple sclerosis and cannabis treatment

Cannabis therapy has been proven to be great for the treatment of muscle stiffness in patients with multiple sclerosis MS. More recently it has been discovered that tetrahydrocannabinol (THC) and cannabidiol (CBD) extracts have the potential to be therapeutic to people with symptoms of multiple sclerosis with little side effects. THC and CBD are the main constituents of the cannabis plant, and the first gives a psychoactive effect. Medical cannabis is currently being used in the united states to treat people with MS. This paper will look at how the combination of THC and CBD can treat MS symptoms such as muscle spasticity.

Here is the full scientific article if you wish to download it.

Main Points

  • Cannabis can reduce spasticity pain
  • Cannabis does not reduce spasticity

Cannabis can reduce spasticity pain

Cannabis is found to have an antispastic effect and this has been shown through a demonstration of inhibitory properties in THC and CBD that affect the cannabis receptors found in the central nervous system. Early studies have focused on the safety of cannabis use in patients with MS and the side effects THC might have on the body. It was then concluded that THC has an intoxicating effect, however it can be therapeutic in treating multiple sclerosis.

Cannabis does not reduce spasticity

It has already been demonstrated that cannabis and its constituents have the power to reduce pain from MS related symptoms such as spascity however it was shown that CBD does not reduce overall spasticity. There were conflicting results in this study because of different assessment measures. There were different dosage levels were applied to each of the animal models, however the general result indicated that pain from muscle spasms was reduced but not overall spascity.


This study has given clear evidence that cannabinoids withhold a neuroprotective and anti inflammatory property that can be beneficial for patients with MS. Inflammation in the brain from the autoimmune disease, MS, has been reduced by cannabinoids through the control of cytokine levels in microglial cells. This study has proven that cannabinoids have a therapeutic effect in treating MS, however more research needs to be carried out to look at how cannabinoids can actually cure spasticity in MS patients.

Jonathan Neilly
Jonathan Neilly
Jonathan Neilly is registered with the British Psychological Society, breaking the taboo on mental health issues is one of the driving forces in his life. His background in biomedicine gives him additional understanding of the factors that work together to influence the human condition.

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