Cannabinoids Pharmacodynamic and Pharmacokinetic Potential | cannabisMD

Cannabinoids Pharmacodynamic and Pharmacokinetic Potential

Cannabinoids Pharmacodynamic and Pharmacokinetic Potential


Tetrahydrocannabidiol (THC) is one of the main constituents of Cannabinoids. Cannabinoids are a group of chemicals derived from the cannabis plant (cannabis sativa). THC has psychoactive effects and this is why the cannabis plant is outlawed in most countries. Cannabidiol (CBD) is another constituent of the marijuana plant and is said to show promise to be made into a therapeutic drug to treat a range of diseases such as cancer and MS. This paper will look at how cannabis can be administered, it’s side effects and what it can treat.

Here is the full scientific article if you wish to download it.

Main Points

  • Cannabis administration
  • Side effects of cannabis
  • What can cannabis treat?

Cannabis administration

Natural cannabis can be inhaled or taken orally, through the rectal passage, sublingual, transdermal administration, eye drops and also aerosols. THC can work differently in the body depending on how it is administered.THC can cause maximum plasma concentration within a minute of inhaling it in a marijuana cigarette and psychotropic effects can happen in this time as well. THC psychotropic effects last for 2-3 hours and peak around the half hour mark. Oral administration can see the psychotropic effects delayed up to 90 minutes and could last for 12 hours depending on how much is taken.

Side effects of cannabis

Medical cannabis is known to have a few side effects when the normal threshold is exceeded. These adverse events include anxiety and panic attacks due to increased heart rate and changes in blood pressure. A tolerance can be built up with regular use of cannabis and this can lead to mild withdrawal syndrome. Cannabis has been a controversial drug as it is not quite known how it affects the psyche long term in regard to cognitive thinking, immune system function and pregnancy.

What can cannabis treat?

It is known that cannabis has an anti inflammatory effect on animal cells and this can lead to analgesia, muscle relaxation, immunosuppression, sedation, improvement of mood, stimulation of appetite, antiemesis, lowering of intraocular pressure, bronchodilation, neuroprotection and induction of apoptosis in cancer cells.

Leave a Reply

Your email address will not be published. Required fields are marked *