Cannabinoids inhibit human keratinocyte proliferation through a non-CB1/CB2 mechanism and have a potential therapeutic value in the treatment of psoriasis.
Psoriasis is a skin condition which is associated with flaky, red patches that appear on the skin. Generally, these patches appear on elbows, knees, back and scalp, however, it is possible that they can appear anywhere else on the body, but they are more susceptible to these areas.
Psoriasis is a long-lasting disease that can be chronic in some cases. Psoriasis is when someone has an increased production of skin cells. People with Psoriasis make and replace skin cells in 3 to 7 days when it usually takes someone an average of 3 to 4 weeks.
Cannabinoids, such as CBD (cannabidiol) and THC (-trans-Δ⁹-tetrahydrocannabinol) are well known as having anti-inflammatory properties and an inhibitive effect on many recurring skin problems. This is because it interacts with tumorigenic cell lines, which are present in human skin and are linked to the symptoms of a variety of skin diseases including Psoriasis.
Psoriasis is an inflammatory disease that is characterized in part by epidermal keratinocyte hyperproliferation. This is linked to the human body’s endocannabinoid system, this is what allows CBD, a cannabinoid to help control the symptoms of psoriasis.
Cannabinoid receptors are present in the human skin, allowing CBD to be directly applied as a topical ointment. When this is done CBD connects to the endocannabinoid receptors and begins to exert its anti-inflammatory properties.
All the cannabinoids tested helped inhibit the severity of psoriasis on the patient’s skin, showing that a topical CBD cream may help patients control their symptoms and have less frequent breakouts. If you wish to use medical cannabis or CBD oil (cannabidiol) as a form of treatment for Psoriasis you should speak with your doctor or medical professional before doing so.