Cannabinoids in the Treatment of Mutliple Sclerosis | cannabisMD

Cannabinoids in the Treatment of Mutliple Sclerosis

Mutliple Sclerosis and Cannabinoids

Cannabinoids are a collection of chemicals that come from the cannabis plant (cannabis sativa). Cannabidiol (CBD) is one of these chemicals and research has said it has anti-inflammatory effects when induced on animal cells.

Tetrahydrocannabinol (THC) is another one of these chemicals that gives off a psychotropic effect in animals brains. Cannabinoid receptors (CB1 and CB2) are found in the endocannabinoid system and allow cannabinoids to bind and work in the body. This paper will look at how cannabinoids could be used in the treatment of the medical condition multiple sclerosis (MS).

Here is the full scientific article if you wish to download it.

Main Points

  • Cannabinoids have been targeted for MS treatment
  • Cannabinoids relieved spasticity in mice

Cannabinoids Have Been Targeted for MS Treatment

Chronic relapsing experimental allergic encephalomyelitis (CREAE) is an autoimmune type of multiple sclerosis in animals.

“These disorders are described by relapsing paralytic episodes, after CREAE introduction by a sharpening of myelin antigens Biozzi ABH mice also gain spasticity and tremor”.

These disorders happen during the onset of multiple sclerosis and are hard to regulate. This has led to people looking for different remedies, and receive the benefits of using cannabis. Clinical studies have approved this advantage of using medical marijuana, however, the therapeutic value of cannabis is still anecdotal.

Cannabinoids Relieved Spasticity in Mice

This paper shows that cannabinoid receptor agonists R(+)-WIN 55,212, Δ 9-tetrahydrocannabinol, methanandamide and JWH-133 can reduce tremor and spasticity in dead mice. The decreasing of disease progression after inducing agonists of cannabinoid receptors 1 and 2, particularly the 1st cannabinoid receptor, show that the endocannabinoid system might be quite active in the regulation of tremor and muscle spasticity.

This gives a reason for cannabinoid selection to certain people for the therapeutic abilities of cannabis in the treating of MS symptoms. However, please consult your doctor nd research the laws regarding cannabis in the area you live.

Jonathan Neilly
Jonathan Neilly
Jonathan Neilly is registered with the British Psychological Society, breaking the taboo on mental health issues is one of the driving forces in his life. His background in biomedicine gives him additional understanding of the factors that work together to influence the human condition.

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