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Cannabinoids are derived from the cannabis plant and is a group of chemicals that include tetrahydrocannabinol (THC) and cannabidiol (CBD). Both of these chemicals are said to have anti inflammatory effects in animal cells. There is a massive therapeutic potential in cannabis and oils that are derived from it for neurological disorders. This has forced cannabis to become legal in certain places around the world, such as california in the united states and holland. This paper will look at preclinical and clinical studies on the potential of cannabinoids to be used therapeutically to treat movement disorders.
Here is the full scientific article if you wish to download it.
Endocannabinoid system modulates neurotransmission
The properties of medical marijuana is strange as it has over 60 neuroactive chemicals within and each are hard to identify from each other. The endocannabinoid system changes neurotransmission that relates to motor function, specifically in the basal ganglia. Preclinical studies in animal experiments of movement disorders have demonstrated varied results for symptomatic advantages but a lot more consistently, suggesting its potential neuroprotective abilities in diseases such as parkinson’s disease and huntington’s.
Cannabinoids have a therapeutic potential
Controlled studies have demonstrated the effectiveness of cannabinoids in therapy suggesting a potential benefit of cannabinoids in tremors of multiple sclerosis or dyskinesia in parkinson’s. There still needs more studies into the potential of cannabinoids in the above mentioned diseases as clinical experiments have come up with conflicting results in the therapeutic effects in MS patients.