Cannabidiol Products as a Promising Treatment for Acne | cannabisMD

Cannabidiol Products as a Promising Treatment for Acne

Cannabidiol Products as a Promising Treatment for Acne

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Seeking new acne treatment from natural products, devices and synthetic drug discovery

The use of safe alternative treatments for acne is important since the conventional therapies are usually associated with adverse effects on the skin or some body organs. Utilising Cannabidiol treatment for acne seems to provide promising outcomes, yielding efficient approaches with minimal side effects.

Main Points

  • The need of targeting acne using effective and safe approaches
  • Cannabidiol as a suitable candidate
  • Other potential treatments

The need of targeting acne using effective and safe approaches

Acne is one of the most common skin conditions that affects the sebaceous glands, in which certain parts of the skin are clogged with dead skin cells, bacteria, and excessive oil production. Acne patients usually experience whiteheads, blackheads, or oily skin patterns. The disease is essentially affected by four main factors, including excessive sebum, inflammation, keratin accumulation, and presence of bacteria. The adequate treatment of acne should target at least one of these processes, with the priority to those therapies that may exert a salutary effect on multiple pathogenic factors. Nonetheless, the latter would have severe side effects. Therefore, cannabidiol treatment for acne has been recently investigated by several studies.

Cannabidiol as a suitable candidate

Cannabidiol (CBD) is found in the cannabis plants and is considered the most beneficial non-psychoactive cannabinoid. Plant-derived CBD has potent analgesic and anti-inflammatory effects, rendering it as an ideal candidate for the treatment of acne. A recent study published in 2018 revealed that CBD can affect the cells that have a lipogenic action by stopping their secretions as well as inhibiting their proliferation and inflammation. As it has no major side effects, cannabidiol treatment for acne can be considered a promising solution for all age categories.

Other potential treatments

In the same study, other natural solutions for acne treatment, such as lupeol and some medicinal plants, provided multi-targeted actions against sebum producing cells. Synthetic agents, including Pentobra antibiotic and nitric oxide-releasing nanoparticles, have also a potent action against acne bacteria. Finally, cryolysis, selective laser-assisted heating and destruction of the sebaceous gland (photothermolysis) and the use of illuminating substances along with handling acne lesions by the light (photodynamic therapy) are all potential novel approaches for acne.


Cannabidiol treatment for acne offers an effective solution with minimal adverse effects. The efficacy of cannabidiol should be investigated on a large-scale with adequate comparison to other proposed natural, synthetic and procedural acne therapies.


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