Is CBD Sebostatic and Anti-Inflammatory? | cannabisMD

Cannabidiol Exerts Sebostatic and Anti-inflammatory Effects

Exerting Sebostatic and Anti-inflammatory Effects with Cannabidiol

Image Credit: Mohammad Bagher Adib Behrooz on Unsplash on Unsplash

This study was approved by the Institutional Research Ethics Committee of the University of Lübeck. The study was set out to explore the effects on cannabis Sativa’s nonpsychoactive chemical compound had medical effects in treating Acne vulgaris (acne) i.e the human sebaceous gland function. When the sebaceous glands become clogged, this can cause acne.

Here is the full scientific article if you wish to download it.

The study states that the exact pharmacokinetics of CBD in the body is still unknown as there is still little to no data on Sativex (a cannabis-derived and synthetic drug). Moreover, the study suggests that CBD can may well have therapeutic concentrations on the sebaceous glands. Researchers also state that a topical form, such as a CBD infused cream might be more beneficial than smoking cannabis. Cannabis dosing is also an important factor in treating acne with cannabis and is something that should not be overlooked.

CBD also exerted complex antiinflammatory actions that were coupled to A2a adenosine receptor-dependent upregulation of tribbles homolog 3 (TRIB3) and inhibition of the NF-κB signaling. Collectively, the findings suggest that, due to the combined lipostatic, antiproliferative, and anti-inflammatory effects, CBD has potential as a therapeutic agent for the treatment of acne vulgaris.

The study is intriguing and it encourages future study on cannabis and whether systemic and or topical CBD cream is a better form of treatment for acne. The study also promotes more in-depth studies on cannabis as a potential treatment for acne and a range of other medical conditions. It’s good to note that, cannabis and its side effects are still relatively unknown and as a result, it’s made clear that more in-depth studies are needed.

If you wish to use medical cannabis or CBD (cannabidiol) as a form of treatment for acne or any other medical condition, it’s important that you first consult your doctor.

Jonathan Neilly
Jonathan Neilly
Jonathan Neilly is registered with the British Psychological Society, breaking the taboo on mental health issues is one of the driving forces in his life. His background in biomedicine gives him additional understanding of the factors that work together to influence the human condition.

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