Are Any CBD Side Effects Serious or Long-Term | cannabisMD

Are Any CBD Side Effects Serious or Long-Term?

CBD Side Effects

If you are using Cannabidiol (CBD), it is essential to take note and be aware of its side effects. Side effects of CBD may vary by user, depending on illnesses, tolerance, and age. Cannabidiol is one of over 80 cannabinoids found in the cannabis plant. The effectiveness of cannabidiol varies by user. However, the drug has been used to treat conditions ranging from chronic pain to Parkinson’s Disease. Studies suggest that CBD has a range of health benefits. Unlike its infamous cousin, Δ⁹-tetrahydrocannabinol (THC), CBD is not psychoactive. CBD acts on our endocannabinoid system (ECS).

The ECS is a bodily system that. When properly balanced with cannabinoids, it offers the body homeostasis and relief. There are two primary cannabinoid receptors: The CB1 receptor and the CB2 receptor. The cannabinoids that maintain the ECS include our own endocannabinoids and those from the cannabis sativa plant. This article outlines the side effects of CBD that a person may experience after ingestion. The side effects of CBD are rare and experience varies by user. More side effects are only seen at high doses and can be fixed with proper dosage. Bodily response may differ depending on:

  • Side effects
  • How bad these side effects are
  • The number of side effects
  • How to take CBD Safely

The reported side effects include:

Heart rate changes – Patients who are using CBD might experience cahnges in heart rate. This is because most find that CBD promotes relaxation, calmness, and dizziness. If you are under the influence of CBD, your heart rate and blood pressure drop. Everyone who is using CBD may not experiences a lower heart rate. Some, in contrast, experience an increased heart rate.

Appetite reduction – THC promotes appetite or food intake. In contrast to the infamous THC, CBD reduces appetite. A study, published In the United States, hypothesizes that CBD regulates appetite by relieving the feeling of food cravings. If you are using CBD, you mmight feel not hungry at all, or it feels like you are full even without eating. This can drive you to lose weight. Experiments suggested that Cannabidiol reduces food intake. When you are using CBD, you might feel like you aren’t hungry. You may lose weight. For some this a plus. For others, who require weight gain, this can be dangerous.

Depression – A few people might experience an episode of depression while using CBD. This depression might result from neurochemical incompatibility with CBD. This would occur if the brain chemistry of the user doesn’t function effectively on CBD. This could cause them to become depressed. Depressive episodes from using CBD could be due to down-regulation of CNS activation. Users who develop depression tend to experience exhaustion.

Cognitive Impairment: CBD could improve cognitive function. This is the case in people with anxiety disorders. However, CBD may also impact some users with cognitive impairment. The impairment may reduce arousal to the point you become tried/drowsy. You might encounter difficulties, including:

  • Concentrating
  • Learning new things
  • Memorizing things
  • Problem-solving
  • Critical thinking

It is recommended when you start using CBD, you don’t involve yourself in demanding tasks that require critical thinking or operating heavy machinery. This is just until you understand how CBD personally affects you.

Brain Fog – You may experience the side effect of impaired mental clarity while using CBD. Brain fog occurs either due to the down-regulation of the sympathetic nervous system or up-regulation of the parasympathetic nervous system.

Dry-mouth – CBD causes dry-mouth for most users. Dry mouth happens because CBD may interact with the salivary gland. We know that human salivary glands have cannabinoid receptors. CBD decreases or reduces saliva production. This can cause you to experience dry mouth. Dry mouth can increase the level of bad bacteria which can cause tooth cavities. If you are having dry-mouth because of CBD, experts recommend you get a regular dental checkup.

Diarrhea – This is the most user-listed common side effect of using CBD. You can talk to your doctor if it is possible to take Imodium or other medication for diarrhea. These can work as counteracting agents.

Drowsiness/tiredness – CBD can cause fatigue. This is because CBD can reduce the activiy in the sympathetic nervous system and upregulate the activation of the parasympathetic nervous system. This leads to a feeling of tiredness and drowsiness. If CBD makes you feel this way, avoid taking it when you are required to drive or do a task that involves critical thinking. These avoidances are for your safety.

Irritability – This could trigger irritation, moodiness, and even depression. Some users may become irritated. This may be true even with small things. The irritation comes from drowsiness, brain fog, and cognitive impairment.

Though they are rare, the side effects listed above require full attention. It is essential to take note that the above information is incomplete. This means we require further research. The above-mentioned side effects can affect your day-to-day activities. Before trying CBD products, speak to your doctor.

These side effects may lead to complications or damage. Side effects from using CBD are a serious matter. If left untreated, CBD could be more damaging than good. Being aware of it possible side effects may help you cope up with any negative result. It is important to work with your trusted physician before and while using CBD. You should also speak to a medical professional if you are planning on starting a new treatment.

Niamh Tumilty
Niamh Tumilty
Niamh Tumilty is a writer and multimedia producer for cannabisMD where she is constantly evaluating the continued growth of CBD and its presence in the news. Her research and writing on cannabis and CBD can be found at

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