Cannabinoids are a neutral group of compounds that are located in the marijuana plant (cannabis sativa). These cannabinoids contain two main chemicals ones are tetrahydrocannabinol (THC) and cannabinol (CBD). Tetrahydrocannabinol (THC) is the main psychoactive part in marijuana and makes you get that the stoned feeling when induced into the endocannabinoid system. Cannabidiol (CBD) is the other main part of ingredient in the cannabis plant and it is illustrated to hold neuro-secure and anti inflammatory functionalities to limit the impacts or treat the effects of neuropathic pain and multiple sclerosis.
The endogenous cannabinoid network is the location throughout the body where cannabinoid receptors, mainly 1 and 2, allow cannabinoids to thrive in the body. Cannabis has a massive potential in cancer as it has the above mentioned properties. Cannabis has been said to be therapeutic in chemotherapy related nausea and vomiting.
This paper will look at how marijuana can affect people with cancer and how cannabinoids could be possibly used to treat people with cancer.
Medical marijuana is somewhat efficient in nausea and vomiting that is brought on by chemotherapy and might be the reason why people treat themselves anecdotally with cannabis when cancer related symptoms come on. Previous research has discovered cannabinoids to be more efficient than a few normal antiemetics such as promethazine in mediating chemotherapy related nausea and vomiting, but these are applied less frequently because of side impacts involving vertigo, dysphoria, and hallucinations. Long-term marijuana application may pay heed to nausea and vomiting, a disorder called cannabinoid hyperemesis syndrome.
A previous review in 2016, has said that cannabinoids were potentially efficient in curing chemotherapy-induced nausea in young adults, but with a great adverse event face (mainly drowsiness, dizziness, modulated moods, and great appetite). Less common adverse events were “ocular issues, orthostatic hypotension, muscle jerking, hallucinations, dizziness and cottonmouth”. There isn’t enough data to display a good opinion about the safety of medical marijuana. Normally, side effects of medicinal marijuana application is not severe, they involve fatigue, more of a hunger and cardiovascular effects. Tolerance to these impacts advances over a timeframe of days or weeks.
The abundance of marijuana usually used for medicinal reasons is not believed to cause any massive cognitive disorders in adults, though long-term treatment in adolescents should be sized carefully as they are more susceptible to these disorders. Departure signs are rarely a issue with mediated medical dosing of cannabinoids.
Cancer researchers from the american cancer society need to conduct more research to evaluate the effects of cannabis on cancers that included in different parts of the body such as breast cancer, lung cancer, prostate cancer and colon cancer. Overall the application of cannabinoid receptor agonists and/or substances inducing endocannabinoid degradation may not only delay the development of tumors by way of numerous mechanisms, but also reduce at the same time, the weight reduction, nausea and pain that so negatively impacts the life of women and men in pain from cancer. As numerous and different methods are more and more likely to solve successfully the problem of cancer treatment, one can only wish for the further pre-clinical and clinical studies that is without a doubt required to point at the idea that will give ever more encouraging conclusions in to understanding of cannabis’ role in cancer.