All of Your Dronabinol Questions Answered at Last | cannabisMD

All of Your Dronabinol Questions Answered at Last

All of Your Dronabinol Questions Answered at Last

Marinol and Syndros are the trade names of Dronabinol. They are a registered trademark of Solvay Pharmaceutical. Dronabinol is a synthetic form of tetrahydrocannabinol (THC). In other words it is a human-made form of the psychoactive compound found in cannabis. The medicine is approved by the FDA to treat loss of appetite in people with AIDS and as an antiemetic (treating nausea and vomiting) for cancer patients that are undergoing chemotherapy.

Dronabinol is the INN (International Nonproprietary Name) for a pure isomer of THC, which is the main cannabinoid found in cannabis. Many cannabinoid medications are approved in the United States, including Dronabinol. The Drug Enforcement Administration issued the final rule of statement and policy on May 13 1896, authorizing and rescheduling synthetic dronabinol.

Dronabinol was manufactured and marketed by PAR Pharmaceutical Companies under the terms of a license and distributional agreement with SVC Pharma LP. SVC Pharma LP is an affiliate of AbbVie Inc (for Marinol) and Insys Pharmaceutical (for Syndros). The medicine is available as a prescription drug in several countries including:

  • Germany
  • South Africa
  • the United States
  • Australia

In The United States, Marinol is considered a non-narcotic and has a low risk of mental or physical dependence.

Directions for Using Dronabinol
The primary use of Dronabinol is to treat nausea and vomiting caused by chemotherapy. Nausea is the feeling of uneasiness in the stomach that often comes before vomiting. The secondary is as an appetite stimulant for people with low appetite and weight loss caused by AIDS. The medication works by affecting the area of people’s brain that controls vomiting, nausea, and appetite. Dronabinol comes as a liquid solution or a capsule and is taken orally.

The medication is usually taken 1 to 3 hours before undergoing chemotherapy and then again 2 to 4 hours after. Patients take a total of 4 to 6 doses a day. Usually the first dose of the solution is taken on an empty stomach at least 30 minutes before eating. After the first, the other doses can be made either without or with food.

When Dronabinol is taken to increase appetite, it is usually taken twice a day about an hour before lunch and dinner. Take Dronabinol as directed for your safety. Be sure to follow your prescription label. If you have further questions, don’t hesitate to ask the pharmacist or talk to your doctor. Note the following directions:

  • Swallow the dronabinol solution with a full glass of water
  • Swallow the dronabinol capsules whole. Do not chew or crush them
  • Use the oral dosing syringe that comes with dronabinol solution to measure your dose

If you have any questions or queries, a physician can easily clarify. They likely will start you on a low dose of dronabinol and gradually increase it as necessary. Your doctor also might decrease your dose if you experience some negative side effects. Be sure to tell your doctor about how you feel during your treatment while using dronabinol.

Precautions
Before taking dronabinol, you should:

  • Tell your doctor if you have an allergy, particularly to sesame oil, and ask the Pharmacists for the list of ingredients
  • Keep your doctor well-informed of how you are feeling, both physically and mentally
  • If you are using or taking disulfiram, antabuse ,or metronidazole, and you have stopped using dronabinol medication within at least fourteen days, your doctor might tell you not to take any of these. You should wait seven days to take disulfiram or metronidazole when or if you stop using dronabinol.
  • Inform your pharmacist or doctor of any prescription or nonprescription medication, nutritional supplements, herbal products, muscle relaxants, or any kind of medicine you are taking or plan to take. This ensures that your doctor is able to prevent potential negative drug interactions while using dronabinol.
  • Tell your doctor if you use or have used drugs, including alcohol
  • Tell your doctor your past medical history, particularly if you ever had heart disease, seizures, high blood pressure or mental illness.
  • Tell your doctor prior to taking dronabinol if you are pregnant or plan to become pregnant. During pregnancy, dronabinol, marinol or sydros, can have adverse effects.
  • Do not breastfeed your child while taking dronabinol
  • Tell your doctor that you are taking dronabinol if you are planning to undergo surgery
  • Be aware that dronabinol makes you drowsy and changes your mood, behavior, thinking, memory and judgment especially at the very beginning of your treatment.
  • Do not drive, operate machinery, or undertake any task that requires mental alertness until you can determine how the medicine affects you.
  • Refrain from drinking liquor or other alcoholic beverages

Possible Side Effects

  • Nausea
  • Memory loss
  • Anxiety
  • Confusion
  • Sleepiness
  • Unsteady walking
  • Hallucination
  • Depression
  • Unusual thoughts
  • Vision problems
  • High
  • Stomach Pain
  • Seizure
  • Fast heartbeat
  • Fainting
  • Dronabinol may cause lightheadedness, dizziness, and fainting when you get up too quickly from lying position.

Medication Storage and Disposal

  • Keep the medicine in the container, closed tightly, and put in place out of reach of children
  • Store capsule in a cool place, about 46-49 degree Fahrenheit or 8- 15 degree Celsius
  • Do not allow the capsule to freeze
  • Once opened, the dronabinol solution can be stored at room temperature for about twenty-eight days.
  • Keep dronabinol away from the heat, light, and moisture

Correct disposal of unneeded medication, especially dronabinol, is essential to ensure that children, pets, and vulnerable people cannot consume it. It is also necessary to know the drug should not be flushed down the toilet. If possible, do the medicine take-back program. You can also contact your local garbage/recycling program to ensure that the medication is disposed of correctly.

Symptoms of Overdose

  • Red eyes
  • Dry mouth
  • Fast heartbeat
  • Memory problems
  • Difficulty in urinating
  • Extreme tiredness
  • Difficulty speaking clearly
  • Constipation
  • Change in awareness of time

To report side effects while using the medication, call your doctor or pharmacist immediately. In case of an emergency such as overdose, call the poison helpline, or call the emergency service at 911.

If you take dronabinol, be sure to follow the directions on your prescription label and take note not to use the medicine more or less than the amount prescribed. Read all patient information, instruction sheets, or medication guides provided to you.

For non-emergencies, your pharmacist also has information you may need about dronabinol. Dronabinol is only permissible for medical use. Following medical directions correctly is crucial to cope up with any illness. Make yourself well-informed regarding any medication you are taking.

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